Overview

  • Product name
  • Description
    Rabbit polyclonal to GPR177
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Full length protein corresponding to Mouse GPR177.
    Database link: Q6DID7

  • Positive control
    • E10.5 mouse telencephalic vessicle tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab176376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1000 - 1/5000.

Requires antigen retrieval - 100mM boiling Tris pH9.

Target

  • Function
    Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
  • Sequence similarities
    Belongs to the wntless family.
  • Cellular localization
    Golgi apparatus membrane. Cytoplasmic vesicle membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • C1orf139 antibody
    • DKFZp686I0788 antibody
    • Evenness interrupted, Drosophila, homolg of antibody
    • EVI antibody
    • FLJ23091 antibody
    • G protein coupled receptor 177 antibody
    • GPR 177 antibody
    • Integral membrane protein GPR177 antibody
    • MGC131760 antibody
    • MGC14878 antibody
    • mig-14 antibody
    • MRP antibody
    • Protein evenness interrupted homolog antibody
    • Protein wntless homolog antibody
    • Putative NF-kappa-B-activating protein 373 antibody
    • Putative NFkB activating protein 373 antibody
    • WLS antibody
    • WLS_HUMAN antibody
    • wntless homolog (Drosophila) antibody
    • Wntless homolog antibody
    • wntless Wnt ligand secretion mediator antibody
    • Wntless, Drosophila, homolog of antibody
    see all

Images

  • Immunohistochemical analysis of frozen section of E10.5 mouse telencephalic vessicle tissue, labeling GPR177 with ab176376 at 1/1000 dilution, followed by Alexafluor goat anti-rabbit secondary. Sections are co-stained with DAPI nuclear stain.

References

This product has been referenced in:
  • Tan SH  et al. Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation. Proc Natl Acad Sci U S A 111:E5262-71 (2014). IHC-Fr ; Mouse . Read more (PubMed: 25422448) »
See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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