Overview

  • Product name

  • Description

    Rabbit polyclonal to GPR177/WLS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Frmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Full length protein corresponding to Mouse GPR177/WLS.
    Database link: Q6DID7

  • Positive control

    • E10.5 mouse telencephalic vessicle tissue.
  • General notes

     This product was previously labelled as GPR177

     

Properties

Applications

Our Abpromise guarantee covers the use of ab176376 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/1000 - 1/5000.

Requires antigen retrieval - 100mM boiling Tris pH9.

Target

  • Function

    Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
  • Sequence similarities

    Belongs to the wntless family.
  • Cellular localization

    Golgi apparatus membrane. Cytoplasmic vesicle membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C1orf139 antibody
    • DKFZp686I0788 antibody
    • Evenness interrupted, Drosophila, homolg of antibody
    • EVI antibody
    • FLJ23091 antibody
    • G protein coupled receptor 177 antibody
    • GPR 177 antibody
    • Integral membrane protein GPR177 antibody
    • MGC131760 antibody
    • MGC14878 antibody
    • mig-14 antibody
    • MRP antibody
    • Protein evenness interrupted homolog antibody
    • Protein wntless homolog antibody
    • Putative NF-kappa-B-activating protein 373 antibody
    • Putative NFkB activating protein 373 antibody
    • WLS antibody
    • WLS_HUMAN antibody
    • wntless homolog (Drosophila) antibody
    • Wntless homolog antibody
    • wntless Wnt ligand secretion mediator antibody
    • Wntless, Drosophila, homolog of antibody
    see all

Images

  • Immunohistochemical analysis of frozen section of E10.5 mouse telencephalic vessicle tissue, labeling GPR177/WLS with ab176376 at 1/1000 dilution, followed by Alexafluor goat anti-rabbit secondary. Sections are co-stained with DAPI nuclear stain.

References

This product has been referenced in:

  • Tan SH  et al. Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation. Proc Natl Acad Sci U S A 111:E5262-71 (2014). IHC-Fr ; Mouse . Read more (PubMed: 25422448) »
See 1 Publication for this product

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