Key features and details
- Chicken polyclonal to GPR177/WLS
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgY
Product nameAnti-GPR177/WLS antibody
See all GPR177/WLS primary antibodies
DescriptionChicken polyclonal to GPR177/WLS
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
This product was previously labelled as GPR177
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityProtein L purified
Our Abpromise guarantee covers the use of ab72385 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/2000 - 1/5000. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).|
FunctionRegulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development.
Sequence similaritiesBelongs to the wntless family.
Cellular localizationGolgi apparatus membrane. Cytoplasmic vesicle membrane.
- Information by UniProt
- C1orf139 antibody
- DKFZp686I0788 antibody
- Evenness interrupted, Drosophila, homolg of antibody
All lanes : Anti-GPR177/WLS antibody (ab72385) at 1/2000 dilution
Lane 1 : Molecular weight markers
Lane 2 : HEK293 cell lysate transfected with GPR177/WLS-GFP
Predicted band size: 62 kDa
Observed band size: 62 kDa
The HEK293 cell protein lysate contains both transfected GPR177/WLS-GFP fusion protein (75 kDa) and endogenous GPR177/WLS protein (~62 kDa).
ab72385 has been referenced in 1 publication.
- de Groot RE et al. Retromer dependent recycling of the wnt secretion factor wls is dispensable for stem cell maintenance in the Mammalian intestinal epithelium. PLoS One 8:e76971 (2013). WB ; Mouse . PubMed: 24130821