Overview

  • Product name

    Anti-GPR2/CCR10 antibody - Extracellular domain
    See all GPR2/CCR10 primary antibodies
  • Description

    Rabbit polyclonal to GPR2/CCR10 - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Hamster, Cow, Dog, Pig, Monkey, Gorilla, Bat
  • Immunogen

    Synthetic peptide corresponding to Human GPR2/CCR10 (extracellular). (16 amino acid peptide from 2nd extracellular domain)
    Database link: P46092

  • Positive control

    • Human colon, carcinoma and human thymus tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.099% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab219270 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 11 - 44 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
  • Tissue specificity

    Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C C chemokine receptor type 10 antibody
    • C-C chemokine receptor type 10 antibody
    • C-C CKR-10 antibody
    • CC chemokine receptor 10 antibody
    • CC CKR 10 antibody
    • CC-CKR-10 antibody
    • CCR-10 antibody
    • CCR10 antibody
    • CCR10_HUMAN antibody
    • Chemokine (C C motif) receptor 10 antibody
    • G protein coupled receptor 2 antibody
    • G-protein coupled receptor 2 antibody
    • GPR2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human colon, carcinoma tissue labeling GPR2/CCR10 with ab219270 at 44 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human thymus tissue labeling GPR2/CCR10 with ab219270 at 44 µg/ml.

References

ab219270 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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