The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-GPR2/CCR10 antibody (ab3904)
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
C C chemokine receptor type 10
C-C chemokine receptor type 10
CC chemokine receptor 10
CC CKR 10
Chemokine (C C motif) receptor 10
G protein coupled receptor 2
G-protein coupled receptor 2
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
Expressed at high levels in adult testis, small intestine, fetal lung, fetal kidney. Weaker expression was observed in many other adult tissues including spleen, thymus, lymph node, Peyer patches, colon, heart, ovary, peripheral blood lymphocytes, thyroid and spinal cord. Also expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells. Also detected in T-cells and in skin-derived Langerhans cells.
Belongs to the G-protein coupled receptor 1 family.