Key features and details
- Rabbit polyclonal to GPR56
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GPR56 antibody
See all GPR56 primary antibodies
DescriptionRabbit polyclonal to GPR56
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Chimpanzee, Macaque monkey, Gorilla, Orangutan
Full length protein corresponding to Human GPR56 aa 1-693.
MTPQSLLQTTLFLLSLLFLVQGAHGRGHREDFRFCSQRNQTHRSSLHYKP TPDLRISIENSEEALTVHAPFPAAHPASRSFPDPRGLYHFCLYWNRHAGR LHLLYGKRDFLLSDKASSLLCFQHQEESLAQGPPLLATSVTSWWSPQNIS LPSAASFTFSFHSPPHTAAHNASVDMCELKRDLQLLSQFLKHPQKASRRP SAAPASQQLQSLESKLTSVRFMGDMVSFEEDRINATVWKLQPTAGLQDLH IHSRQEEEQSEIMEYSVLLPRTLFQRTKGRSGEAEKRLLLVDFSSQALFQ DKNSSHVLGEKVLGIVVQNTKVANLTEPVVLTFQHQLQPKNVTLQCVFWV EDPTLSSPGHWSSAGCETVRRETQTSCFCNHLTYFAVLMVSSVEVDAVHK HYLSLLSYVGCVVSALACLVTIAAYLCSRVPLPCRRKPRDYTIKVHMNLL LAVFLLDTSFLLSEPVALTGSEAGCRASAIFLHFSLLTCLSWMGLEGYNL YRLVVEVFGTYVPGYLLKLSAMGWGFPIFLVTLVALVDVDNYGPIILAVH RTPEGVIYPSMCWIRDSLVSYITNLGLFSLVFLFNMAMLATMVVQILRLR PHTQKWSHVLTLLGLSLVLGLPWALIFFSFASGTFQLVVLYLFSIITSFQ GFLIFIWYWSMRLQARGGPSPLKSNSDSARLPISSGSTSSSRI
Database link: AAH08770.1
- GPR56 transfected 293T cell lysate
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Constituent: 100% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab172361 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa.|
FunctionCould be involved in cell-cell interactions.
Tissue specificityWidely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
Involvement in diseasePolymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
modificationsThe endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
Cellular localizationCell membrane.
- Information by UniProt
- 7 transmembrane protein with no EGF like N terminal domains 1 antibody
- BFPP antibody
- DKFZp781L1398 antibody
All lanes : Anti-Doublecortin antibody [EPR10936] (ab172631) at 1/1000 dilution
Lane 1 : GPR56 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Predicted band size: 78 kDa
ab172361 has been referenced in 2 publications.
- Ackerman SD et al. GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med 215:941-961 (2018). PubMed: 29367382
- Song Y et al. Expression of G protein-coupled receptor 56 is associated with tumor progression in non-small-cell lung carcinoma patients. Onco Targets Ther 9:4105-12 (2016). WB, ELISA ; Human . PubMed: 27462165