Overview

  • Product name
  • Description
    Rabbit polyclonal to GPR56
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Hamster, Cow, Dog, Pig, Chimpanzee, Monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human GPR56 (intracellular). (16 amino acid peptide from 1st cytoplasmic domain).
    Database link: Q9Y653

Properties

Applications

Our Abpromise guarantee covers the use of ab174697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 21 µg/ml.

Target

  • Function
    Could be involved in cell-cell interactions.
  • Tissue specificity
    Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
  • Involvement in disease
    Polymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
  • Post-translational
    modifications
    The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 7 transmembrane protein with no EGF like N terminal domains 1 antibody
    • BFPP antibody
    • DKFZp781L1398 antibody
    • EGF TM7 like antibody
    • G protein coupled receptor 56 antibody
    • G-protein coupled receptor 56 antibody
    • GPR 56 antibody
    • Gpr56 antibody
    • GPR56_HUMAN antibody
    • Polymicrogyria bilateral frontoparietal antibody
    • Protein TM7XN1 antibody
    • TM7LN4 antibody
    • TM7XN1 antibody
    • TM7XN1 protein antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human, brain tissue labeling GPR56 with ab174697 at 21 µg/ml.

References

ab174697 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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