Key features and details
- Rabbit polyclonal to GPR56
- Suitable for: WB, ELISA, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GPR56 antibody
See all GPR56 primary antibodies
DescriptionRabbit polyclonal to GPR56
Tested applicationsSuitable for: WB, ELISA, ICC/IFmore details
Species reactivityReacts with: Human
Synthetic peptide derived from the an internal sequence of Human GPR56
- WB: extracts from K562 cells. ICC/IF: MCF-7 cells.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab77515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 78 kDa.|
|ICC/IF||1/500 - 1/1000.|
FunctionCould be involved in cell-cell interactions.
Tissue specificityWidely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
Involvement in diseasePolymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry.
Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
modificationsThe endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
Cellular localizationCell membrane.
- Information by UniProt
- 7 transmembrane protein with no EGF like N terminal domains 1 antibody
- BFPP antibody
- DKFZp781L1398 antibody
All lanes : Anti-GPR56 antibody (ab77515) at 1/500 dilution
Lane 1 : Extracts from K562 cells
Lane 2 : Extracts from K562 cells with immunizing peptide at 5 µg
Lysates/proteins at 15 µg per lane.
Predicted band size: 78 kDa
Observed band size: 78 kDa
Immunofluorescence analysis of MCF-7 cells using 1/500 - 1/1000 ab77515
Left image: untreated.
Right image: after pre-incubation twith immunizing peptide.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab77515 has not yet been referenced specifically in any publications.