Anti-GPR56 antibody (ab88700)
Key features and details
- Mouse polyclonal to GPR56
- Suitable for: WB, Flow Cyt
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPR56 antibody
See all GPR56 primary antibodies -
Description
Mouse polyclonal to GPR56 -
Host species
Mouse -
Tested Applications & Species
Application Species Flow Cyt HumanWB Human -
Immunogen
Full length Human protein
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Positive control
- Stomach lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing the problem with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation.
One factor contributing to the crisis is the use of antibodies that are not suitable. This can lead to misleading results and the use of incorrect data informing project assumptions and direction. To help address this challenge, we have introduced an application and species grid on our primary antibody datasheets to make it easy to simplify identification of the right antibody for your needs.
Learn more here.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Constituent: 2.68% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab88700 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
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Flow Cyt |
Human
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WB |
Human
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Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa.
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|
Flow Cyt |
Use at an assay dependent concentration.
ab37355 - Mouse polyclonal IgG, is suitable for use as an isotype control with this antibody.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 78 kDa. |
Flow Cyt
Use at an assay dependent concentration. ab37355 - Mouse polyclonal IgG, is suitable for use as an isotype control with this antibody.
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Target
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Function
Could be involved in cell-cell interactions. -
Tissue specificity
Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells. -
Involvement in disease
Polymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain. -
Post-translational
modificationsThe endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 9289 Human
- Omim: 604110 Human
- SwissProt: Q9Y653 Human
- Unigene: 513633 Human
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Alternative names
- 7 transmembrane protein with no EGF like N terminal domains 1 antibody
- BFPP antibody
- DKFZp781L1398 antibody
see all
Images
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FACS analysis of negative control 293 cells (Black) and GPR56-expressing 293 cells (Green) using ab88700 at 1ug/ml.
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Anti-GPR56 antibody (ab88700) at 1/500 dilution + Human stomach lysate at 50 µg
Predicted band size: 78 kDa -
All lanes : Anti-GPR56 antibody (ab88700) at 1 µg/ml
Lane 1 : GPR56-transfected 293T cell lysate
Lane 2 : non transfected lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 78 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab88700 has not yet been referenced specifically in any publications.