Overview

  • Product name

  • Description

    Rabbit polyclonal to GPRC5C
  • Host species

    Rabbit
  • Specificity

    Detects endogenous levels of total GPRC5C protein.
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide derived from an internal region of Human GPRC5C

  • Positive control

    • Cos-7 cell extract RAW264.7 cell extract

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS

    Without Mg2+ and Ca2+
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab75499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
ELISA 1/5000.

Target

  • Function

    This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • Tissue specificity

    Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG).
  • Sequence similarities

    Belongs to the G-protein coupled receptor 3 family.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • Database links

  • Alternative names

    • G protein coupled receptor family C group 5 member C antibody
    • G-protein coupled receptor family C group 5 member C antibody
    • GPC5C_HUMAN antibody
    • GPCR5C antibody
    • Gprc5c antibody
    • MGC131820 antibody
    • Orphan G protein coupled receptor antibody
    • RAIG-3 antibody
    • RAIG3 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 3 protein antibody
    see all

Images

  • All lanes : Anti-GPRC5C antibody (ab75499) at 1/500 dilution

    Lane 1 : RAW264.7 cell extract
    Lane 2 : Cos-7 cell extract
    Lane 3 : RAW264.7 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 48 kDa
    Observed band size: 48 kDa
    Additional bands at: 100 kDa. We are unsure as to the identity of these extra bands.

References

ab75499 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab75499.
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