Overview

  • Product name

    Anti-GPS2 antibody
  • Description

    Rabbit polyclonal to GPS2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow
  • Immunogen

    A recombinant protein fragment corresponding to a region within amino acids 1-253 of Human GPS2

  • Positive control

    • A431 and HeLa whole cell lysate (ab150035); Gastric carcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab153986 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 37 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Relevance

    GPS2(G-protein pathway suppressor 2), also called AMF1, is a human nuclear protein of 327 amino acids involved in G protein-mitogen-activated protein kinase(MAPK) signalling cascades. This protein is an integral subunit of the NCOR1-HDAC3(nuclear receptor corepressor 1-histone deacetylase 3) complex which inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1(activator protein 1) function.
  • Cellular localization

    Nuclear
  • Database links

  • Alternative names

    • AMF 1 antibody
    • AMF1 antibody
    • G protein pathway suppressor 2 antibody
    • GPS 2 antibody

Images

  • All lanes : Anti-GPS2 antibody (ab153986) at 1/500 dilution

    Lane 1 : A431 cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 37 kDa



    10% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Gastric Carcinoma labeling GPS2 using ab153986 at 1/500 dilution.

References

ab153986 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab153986.
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