Key features and details
- Selective 5-HT1B / 5-HT1D receptor antagonist
- CAS Number: 172854-55-6
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameGR 55562 dihydrochloride, 5-HT1B / 5-HT1D receptor antagonist
DescriptionSelective 5-HT1B / 5-HT1D receptor antagonist
Selective, competitive 5-HT1B/ 5-HT1D receptor antagonist (pKi values are 7.4 and 6.2, respectively). Inhibits 5-HT evoked contraction in pulmonary resistance arteries (pEC10 = 7.26).
Chemical name3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride
Storage instructionsStore at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120513 has not yet been referenced specifically in any publications.