Overview

  • Product name

    GR113808, selective 5-HT4 antagonist
  • Description

    Potent, highly selective 5-HT4 antagonist
  • Biological description

    Potent, highly selective 5-HT4 receptor antagonist (pKb = 8.8). Displays > 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Decreases water intake and potentiates drinking.
  • Purity

    > 99%
  • CAS Number

    144625-51-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Castro L  et al. Effect of the intracerebroventricular administration of GR 113808, a selective 5-HT4 antagonist, on water intake during hyperosmolarity and hypovolemia. Braz J Med Biol Res 34:791-6 (2001). Read more (PubMed: 11378670) »
  • Gale JD  et al. GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor. Br J Pharmacol 111:332-8 (1994). Read more (PubMed: 8012715) »
  • Kaumann AJ Blockade of human atrial 5-HT4 receptors by GR 113808. Br J Pharmacol 110:1172-4 (1993). Read more (PubMed: 8298805) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120544.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up