Anti-Granzyme M antibody (ab201102)
Key features and details
- Rabbit polyclonal to Granzyme M
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-Granzyme M antibody
See all Granzyme M primary antibodies -
Description
Rabbit polyclonal to Granzyme M -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Granzyme M.
Database link: P51124 -
Positive control
- HeLa, PC12 and sp20 whole cell lysates.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab201102 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab201102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent concentration. Predicted molecular weight: 28 kDa. |
Target
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Function
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. -
Tissue specificity
Highly and constitutively expressed in activated natural killer (NK) cells. -
Sequence similarities
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain. -
Cellular localization
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes. - Information by UniProt
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Database links
- Entrez Gene: 3004 Human
- Entrez Gene: 16904 Mouse
- Entrez Gene: 29252 Rat
- Omim: 600311 Human
- SwissProt: P51124 Human
- SwissProt: Q03238 Rat
- Unigene: 465511 Human
- Unigene: 9838 Rat
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Alternative names
- GRAM_HUMAN antibody
- Granzyme M (lymphocyte met ase 1) antibody
- Granzyme M antibody
see all
Images
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Western blot - Anti-Granzyme M antibody (ab201102)All lanes : Anti-Granzyme M antibody (ab201102)
Lane 1 : HeLa whole cell lysate
Lane 2 : PC12 whole cell lysate
Lane 3 : sp20 whole cell lysate
Predicted band size: 28 kDa
References (0)
ab201102 has not yet been referenced specifically in any publications.
