Anti-Granzyme M antibody (ab201102)

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Overview

  • Product name

    Anti-Granzyme M antibody
    See all Granzyme M primary antibodies

  • Description

    Rabbit polyclonal to Granzyme M

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide corresponding to Human Granzyme M.
    Database link: P51124

  • Positive control

    • HeLa, PC12 and sp20 whole cell lysates.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Purification notes

    ab201102 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab201102 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 28 kDa.

Target

  • Function

    Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

  • Tissue specificity

    Highly and constitutively expressed in activated natural killer (NK) cells.

  • Sequence similarities

    Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.

  • Cellular localization

    Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
  • Information by UniProt

  • Database links

    • Alternative names

      • GRAM_HUMAN antibody
      • Granzyme M (lymphocyte met ase 1) antibody
      • Granzyme M antibody
      • GranzymeM antibody
      • GZM M antibody
      • Gzmm antibody
      • HU Met 1 antibody
      • HU-Met-1 antibody
      • LMET 1 antibody
      • LMET1 antibody
      • Lymphocyte met ase 1 antibody
      • MET 1 antibody
      • Met 1 serine protease antibody
      • Met ase antibody
      • Met-1 serine protease antibody
      • Met-ase antibody
      • MET1 antibody
      • Met1 serine protease antibody
      • Natural killer cell granular protease antibody
      see all

    Images

    • Western blot - Anti-Granzyme M antibody (ab201102)
      Western blot - Anti-Granzyme M antibody (ab201102)
      All lanes : Anti-Granzyme M antibody (ab201102)

      Lane 1 : HeLa whole cell lysate
      Lane 2 : PC12 whole cell lysate
      Lane 3 : sp20 whole cell lysate

      Predicted band size: 28 kDa

    References

    ab201102 has not yet been referenced specifically in any publications.

    Publishing research using ab201102? Please let us know so that we can cite the reference in this datasheet.

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