Anti-Granzyme M antibody (ab201102)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-Granzyme M antibody
See all Granzyme M primary antibodies -
Description
Rabbit polyclonal to Granzyme M -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide corresponding to Human Granzyme M.
Database link: P51124 -
Positive control
- HeLa, PC12 and sp20 whole cell lysates.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.3
Preservative: 0.05% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Purification notes
ab201102 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
-
Related Products
Applications
Our Abpromise guarantee covers the use of ab201102 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | Use at an assay dependent concentration. Predicted molecular weight: 28 kDa. |
Target
-
Function
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. -
Tissue specificity
Highly and constitutively expressed in activated natural killer (NK) cells. -
Sequence similarities
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain. -
Cellular localization
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes. - Information by UniProt
-
Database links
- Entrez Gene: 3004 Human
- Entrez Gene: 16904 Mouse
- Entrez Gene: 29252 Rat
- Omim: 600311 Human
- SwissProt: P51124 Human
- SwissProt: Q03238 Rat
- Unigene: 465511 Human
- Unigene: 9838 Rat
-
Alternative names
- GRAM_HUMAN antibody
- Granzyme M (lymphocyte met ase 1) antibody
- Granzyme M antibody
see all
Images
Protocols
References
ab201102 has not yet been referenced specifically in any publications.