Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.097% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesThis antibody is > 95% pure as assessed by SDS-PAGE
Our Abpromise guarantee covers the use of ab107581 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 38 kDa.|
|IP||Use at an assay dependent concentration.|
|Flow Cyt||Use a concentration of 1 µg/ml.
ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
FunctionInteracts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.
Sequence similaritiesBelongs to the GRB2/sem-5/DRK family.
Contains 1 SH2 domain.
Contains 2 SH3 domains.
- Information by UniProt
- Adapter protein GRID antibody
- GADS antibody
- GADS protein antibody
This product has been referenced in:
- Yankee TM et al. The Gads (GrpL) adaptor protein regulates T cell homeostasis. J Immunol 173:1711-20 (2004). Read more (PubMed: 15265900) »
- Yankee TM et al. CD95/Fas induces cleavage of the GrpL/Gads adaptor and desensitization of antigen receptor signaling. Proc Natl Acad Sci U S A 98:6789-93 (2001). Read more (PubMed: 11391000) »