Overview

  • Product name

    Anti-GRF2 antibody - C-terminal
    See all GRF2 primary antibodies
  • Description

    Rabbit polyclonal to GRF2 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human GRF2 (C terminal). The exact sequence is proprietary. Carrier-protein conjugated.
    Database link: Q13905

  • Positive control

    • WB: K562, THP-1 and HL-60 whole cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab229730 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 121 kDa.

Target

  • Function

    Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.
  • Tissue specificity

    Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
  • Sequence similarities

    Contains 1 N-terminal Ras-GEF domain.
    Contains 1 Ras-GEF domain.
  • Information by UniProt
  • Database links

  • Form

    It localizes to cytoplasm and endosomes.
  • Alternative names

    • C3G antibody
    • C3G protein antibody
    • CRK SH3 binding GNRP antibody
    • CRK SH3-binding GNRP antibody
    • DKFZp781P1719 antibody
    • GRF 2 antibody
    • GRF2 antibody
    • Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody
    • Guanine nucleotide releasing factor 2 antibody
    • Guanine nucleotide-releasing factor 2 antibody
    • OTTHUMP00000064558 antibody
    • Protein C3G antibody
    • Rap guanine nucleotide exchange factor (GEF) 1 antibody
    • Rap guanine nucleotide exchange factor 1 antibody
    • RAPGEF 1 antibody
    • RAPGEF1 antibody
    • RPGF1_HUMAN antibody
    see all

Images

  • All lanes : Anti-GRF2 antibody - C-terminal (ab229730) at 1/1000 dilution

    Lane 1 : K562 (human chronic myelogenous leukemia cell line from bone marrow ) whole cell extract
    Lane 2 : THP-1 (human monocytic leukemia cell line) whole cell extract
    Lane 3 : HL-60 (human promyelocytic leukemia cell line) whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 121 kDa



    5% SDS-PAGE gel.

References

ab229730 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229730.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up