Overview

  • Product name

  • Description

    Rabbit polyclonal to GRIK3/GluK3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human GRIK3/GluK3 aa 69-99 (N terminal) conjugated to keyhole limpet haemocyanin. (NP_000822.2; Q13003)

  • Positive control

    • Mouse stomach tissue lysate; Human kidney tissue
  • General notes

     This product was previously labelled as GRIK3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab129406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 104 kDa.
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA.
  • Sequence similarities

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK3 subfamily.
  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • EAA5 antibody
    • Excitatory amino acid receptor 5 antibody
    • GLR 7 antibody
    • GLR7 antibody
    • GLU R7 antibody
    • GLUR 7 antibody
    • GluR 7a antibody
    • GluR-7 antibody
    • GluR7 antibody
    • GluR7a antibody
    • Glutamate receptor 7 antibody
    • Glutamate receptor antibody
    • Glutamate receptor ionotropic kainate 3 antibody
    • GRIK 3 antibody
    • GRIK3 antibody
    • GRIK3_HUMAN antibody
    • ionotropic kainate 3 antibody
    see all

Images

  • Anti-GRIK3/GluK3 antibody (ab129406) at 1/100 dilution + Mouse stomach tissue lysate at 35 µg

    Predicted band size: 104 kDa

  • ab129406 at a 1/10 dilution staining GRIK3/GluK3 in Human kidney tissue (formalin-fixed, paraffin-embedded). Following primary incubation tissue was stained with peroxidase conjugated secondary antibody and DAB.

References

ab129406 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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