Anti-GRIP1 antibody [GRP01] (ab44970)
Key features and details
- Mouse monoclonal [GRP01] to GRIP1
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-GRIP1 antibody [GRP01]
See all GRIP1 primary antibodies -
Description
Mouse monoclonal [GRP01] to GRIP1 -
Host species
Mouse -
Specificity
This antibody is raised against glutamate receptor-interacting protein 1 -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant GRIP1 protein (Human)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
GRP01 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Target
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Function
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. -
Sequence similarities
Contains 7 PDZ (DHR) domains. -
Domain
PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1 and EPHB2 and with the C-terminus of PPFIA1 and PPFIA4. PDZ 4 and PDZ 5 mediate interaction with the C-terminus of GRIA2 and GRIA3. PDZ 4, PDZ 5 and PDZ 6 mediate homomultimers. PDZ 7 mediates interaction with PDZ domain of GRASP1. PDZ 7 domain binds CSPG4. PDZ 6 mediates interaction with the C-terminus of liprins-alpha. PDZ 1, PDZ 2 and PDZ 3 mediate interaction with the PDZ-binding motif of FRAS1 (By similarity). PDZ 4 and PDZ 5 mediate interaction with PRLHR. -
Cellular localization
Cytoplasmic vesicle. Endoplasmic reticulum. Cell junction > synapse > postsynaptic cell membrane. Cytoplasmic and membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in post-synaptic plasma membrane and post-synaptic densities. - Information by UniProt
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Database links
- Entrez Gene: 23426 Human
- Omim: 604597 Human
- SwissProt: Q9Y3R0 Human
- Unigene: 505946 Human
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Alternative names
- as GRIP antibody
- Glutamate receptor-interacting protein 1 antibody
- GRIP-1 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab44970 has not yet been referenced specifically in any publications.