Overview

  • Product name

    Anti-GRLF1 (phospho Y1087) antibody
    See all GRLF1 primary antibodies
  • Description

    Rabbit polyclonal to GRLF1 (phospho Y1087)
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human GRLF1 aa 1070-1095 (phospho Y1087) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    SVSSSPWLPQDGFDPSDYAEPMDAVV


    Database link: Q9NRY4

  • Positive control

    • Rat brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab203274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

When using a fluorescent probe the recommended dilution is 1/50 – 1/200

Target

  • Function

    Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.
  • Sequence similarities

    Contains 4 FF domains.
    Contains 1 Rho-GAP domain.
  • Post-translational
    modifications

    Tyrosine phosphorylated.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • ARHGAP35 antibody
    • GAP associated protein p190 antibody
    • Glucocorticoid receptor DNA binding factor 1 antibody
    • Glucocorticoid receptor DNA-binding factor 1 antibody
    • Glucocorticoid receptor repression factor 1 antibody
    • GRF 1 antibody
    • GRF-1 antibody
    • GRF1 antibody
    • GRLF 1 antibody
    • GRLF1 antibody
    • GRLF1_HUMAN antibody
    • KIAA1722 antibody
    • MGC10745 antibody
    • p190 A antibody
    • p190-A antibody
    • P190A antibody
    • P190A, rat, homolog of antibody
    • p190ARhoGAP antibody
    • p190RhoGAP antibody
    • Rho GAP p190A antibody
    • Rho GTPase-activating protein 35 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat brain tissue labeling GRLF1 with ab203274 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining

     

References

ab203274 has not yet been referenced specifically in any publications.

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