Key features and details
- Rabbit polyclonal to GRLF1 (phospho Y1105)
- Suitable for: IHC-P, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GRLF1 (phospho Y1105) antibody
See all GRLF1 primary antibodies
DescriptionRabbit polyclonal to GRLF1 (phospho Y1105)
SpecificityThis antibody detects endogenous levels of GRLF1 only when phosphorylated at tyrosine 1105.
Tested applicationsSuitable for: IHC-P, ELISAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide (Human)(Peptide available as ab106616.)
- IHC-P: Human breast carcinoma tissue.
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe antibody was affinity purified from rabbit antiserum by affinity chromatography using epitopespecific phosphopeptide. The antibody against non phosphopeptide was removed by chromatography using non phosphopeptide corresponding to the phosphorylation site.
Our Abpromise guarantee covers the use of ab55339 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.|
FunctionRepresses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3'. May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP). May also act as a tumor suppressor.
Sequence similaritiesContains 4 FF domains.
Contains 1 Rho-GAP domain.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
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ab55339 has been referenced in 1 publication.
- Datta A et al. Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition. Cell Signal 40:91-98 (2017). PubMed: 28888686