Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Constituent: 100% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab194657 was purified by affinity chromatography employing immobilized GRO alpha matrix.
Our Abpromise guarantee covers the use of ab194657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/0.1 - 1/0.2. Predicted molecular weight: 11 kDa.|
|Sandwich ELISA||Use a concentration of 0.5 - 2 µg/ml.
ab194657 in conjunction with an compatible secondary reagent as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant CXCR2.
|Neutralising||Use a concentration of 1.5 - 3 µg/ml.|
FunctionHas chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
modificationsN-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes.
- Information by UniProt
- C-X-C motif chemokine 1 antibody
- Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) antibody
- chemokine (C-X-C motif) ligand 1 antibody
ab194657 has not yet been referenced specifically in any publications.