Overview

  • Product name

    Anti-Growth Hormone antibody
    See all Growth Hormone primary antibodies
  • Description

    Rabbit polyclonal to Growth Hormone
  • Host species

    Rabbit
  • Specificity

    Recognizes bovine growth hormone (BGH): 100%
  • Tested applications

    Suitable for: RIAmore details
  • Species reactivity

    Reacts with: Cow
  • Immunogen

    Full length protein corresponding to Cow Growth Hormone.

Properties

Applications

Our Abpromise guarantee covers the use of ab31496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
RIA
  • Application notes
    RIA: Use at 65000 tests/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
    • Involvement in disease

      Defects in GH1 are a cause of growth hormone deficiency isolated type 1A (IGHD1A) [MIM:262400]; also known as pituitary dwarfism I. IGHD1A is an autosomal recessive deficiency of GH which causes short stature. IGHD1A patients have an absence of GH with severe dwarfism and often develop anti-GH antibodies when given exogenous GH.
      Defects in GH1 are a cause of growth hormone deficiency isolated type 1B (IGHD1B) [MIM:612781]; also known as dwarfism of Sindh. IGHD1B is an autosomal recessive deficiency of GH which causes short stature. IGHD1B patients have low but detectable levels of GH. Dwarfism is less severe than in IGHD1A and patients usually respond well to exogenous GH.
      Defects in GH1 are the cause of Kowarski syndrome (KWKS) [MIM:262650]; also known as pituitary dwarfism VI.
      Defects in GH1 are a cause of growth hormone deficiency isolated type 2 (IGHD2) [MIM:173100]. IGHD2 is an autosomal dominant deficiency of GH which causes short stature. Clinical severity is variable. Patients have a positive response and immunologic tolerance to growth hormone therapy.
    • Sequence similarities

      Belongs to the somatotropin/prolactin family.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • gH antibody
      • GH-N antibody
      • GH1 antibody
      • GHB5 antibody
      • GHN antibody
      • Growth hormone 1 antibody
      • Growth hormone antibody
      • Growth hormone B5 antibody
      • Growth hormone, normal antibody
      • Growth hormone, pituitary antibody
      • HG1 antibody
      • hGH-N antibody
      • IGHD1B antibody
      • Pituitary growth hormone antibody
      • RNGHGP antibody
      • SOMA_HUMAN antibody
      • Somatotropin antibody
      see all

    References

    ab31496 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Question
    Answer

    Thisantibody is neat serum. It has not been purified in any way.

    I apologize for the confusion due to the incorrect information posted on our datasheet. This will be updated ASAP.

    I hope this is helpful. Please contact us again if you have any further questions.

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