Overview

  • Product name

    GSK 0660, PPARdelta antagonist
  • Description

    Selective PPARδ antagonist
  • Biological description

    Selective PPARδ antagonist (IC50 values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively). Active in vivo. Exhibits inverse agonist effects when administered alone.
  • Purity

    > 99%
  • CAS Number

    1014691-61-2
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mikami D  et al. Telmisartan activates endogenous peroxisome proliferator-activated receptor-d and may have anti-fibrotic effects in human mesangial cells. Hypertens Res : (2013). Read more (PubMed: 24352213) »
  • Kapoor A  et al. Protective role of peroxisome proliferator-activated receptor-ß/d in septic shock. Am J Respir Crit Care Med 182:1506-15 (2010). Read more (PubMed: 20693380) »
  • Gill N  et al. Anti-inflammatory and anti-hyperalgesic effect of all-trans retinoic acid in carrageenan-induced paw edema in Wistar rats: involvement of peroxisome proliferator-activated receptor-ß/d receptors. Indian J Pharmacol 45:278-82 (0). Read more (PubMed: 23833373) »

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