Key features and details
- Useful negative control for PAD4 inhibitors GSK-121 and GSK-484.
- CAS Number: 1652591-82-6
- Purity: > 98%
- Soluble in DMSO to 65 mM
- Form / State: Solid
- Source: Synthetic
Product nameGSK-106 hydrochloride, negative control for GSK-121 and GSK-484
DescriptionUseful negative control for PAD4 inhibitors GSK-121 and GSK-484.
- (3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride
Useful negative control for PAD4 inhibitors GSK-121 and GSK-484. Does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC50s > 100 µM).
Chemical name(3-Aminopiperidin-1-yl)(2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzo[d]imidazol-6-yl)methanone hydrochloride
Storage instructionsShipped at 4°C. Store at -20°C. Store under desiccating conditions.
Solubility overviewSoluble in DMSO to 65 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab229184 has not yet been referenced specifically in any publications.