Key features and details
- Selective ERRβγ agonist
- CAS Number: 101574-65-6
- Purity: > 99%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameGSK 4716, ERRbetagamma agonist
DescriptionSelective ERRβγ agonist
Selective ERRβ/γ agonist. Displays selectivity for ERRβ/γ over ERRα/β as well as other classical estrogen receptors. ERRβ is transiently induced and ERRγ is dramatically induced in vitro. Cell-permeable. Increases glucocorticoid receptor (GR) and 11beta-hydroxysteroid dehydrogenase type 1 mRNA in vitro.
Chemical name2-[[4-(1-Methylethyl)phenyl]methylene]hydrazide 4-hydroxybenzoic acid
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120826 has not yet been referenced specifically in any publications.