Overview

  • Product name

    GSK 4716, ERRbetagamma agonist
  • Description

    Selective ERRβγ agonist
  • Biological description

    Selective ERRβ/γ agonist. Displays selectivity for ERRβ/γ over ERRα/β as well as other classical estrogen receptors. ERRβ is transiently induced and ERRγ is dramatically induced in vitro. Cell-permeable. Increases glucocorticoid receptor (GR) and 11beta-hydroxysteroid dehydrogenase type 1 mRNA in vitro.
  • Purity

    > 99%
  • CAS Number

    101574-65-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Wang SC  et al. An ERRbeta/gamma agonist modulates GRalpha expression, and glucocorticoid responsive gene expression in skeletal muscle cells. Mol Cell Endocrinol 315:146-52 (2010). Read more (PubMed: 19631715) »
  • Kim Y  et al. Efficient discovery of selective small molecule agonists of estrogen-related receptor gamma using combinatorial approach. J Comb Chem 11:928-37 (0). Read more (PubMed: 19746993) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120826.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up