Overview

  • Product name

  • Description

    Rabbit polyclonal to GSTA2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human, Monkey
  • Immunogen

    Recombinant fragment within Human GSTA2 aa 1-196. The exact sequence is proprietary.
    Database link: P09210

  • Positive control

    • Human kidney tissue; HepG2 cells; HepG2 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab211449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.
  • Cellular localization

    Cytoplasmic
  • Database links

  • Alternative names

    • EC 2.5.1.18 antibody
    • Glutathione S transferase 2 antibody
    • Glutathione S transferase A2 antibody
    • Glutathione S-alkyltransferase A2 antibody
    • Glutathione S-aralkyltransferase A2 antibody
    • Glutathione S-aryltransferase A2 antibody
    • Glutathione S-transferase alpha 2 antibody
    • Glutathione S-transferase GT41A antibody
    • Glutathione S-transferase Ya-2 antibody
    • Glutathione S-transferase, alpha 2 (Yc2) antibody
    • GST 1b-1b antibody
    • GST A2-2 antibody
    • GST class alpha member 2 antibody
    • GST gamma antibody
    • GST HA subunit 2 antibody
    • GST Ya2 antibody
    • GST, class alpha, 2 antibody
    • GST2 antibody
    • Gst2-2 antibody
    • GSTA2 2 antibody
    • GSTA2-2 antibody
    • Gstc-2 antibody
    • Gstc2 antibody
    • GTA2 antibody
    • GTH2 antibody
    • HA subunit 2 antibody
    • Liver GST2 antibody
    • MGC10525 antibody
    • OTTHUMP00000017883 antibody
    • S-(hydroxyalkyl)glutathione lyase A2 antibody
    see all

Images

  • Anti-GSTA2 antibody (ab211449) at 1/3000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size: 26 kDa



    12% SDS PAGE.

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human kidney tissue labeling GSTA2 with ab211449 at 5μg/mL. 

  • Immunofluorescence analysis of methanol fixed, HepG2 cells labeling GSTA2 with ab211449 at a 1/500 dilution.

References

ab211449 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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