Overview

  • Product name
    GTP (Guanosine-5'-triphosphate)
  • Description
    Purine nucleoside. Essential in many physiological functions.
  • Alternative names
    • Guanosine-5'-triphosphate
  • Biological description
    Purine nucleoside. Essential in many physiological functions including RNA synthesis and cell signaling. Also acts as a metabolic energy source and induces apoptosis.

Properties

  • Chemical name
    Guanosine 5'-triphosphate ammonium salt
  • Molecular weight
    523.18
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C10H16N5O14P3.xNH3
  • CAS Number
    86-01-1
  • PubChem identifier
    6830
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES
    N.N.N.O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n2cnc1c2N=C(N)NC1=O)C(O)[C@H]3O
  • Source

    Synthetic

  • Research areas

References

ab120628 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Microtubules (MT) were isolated from SH-SY5y cells using 0.1mM GTP and Paclitaxel (ab120143) as per the protocol outlined in: Sloboda RD. 2014b. Isolation of microtubules and microtubule-associated proteins using paclitaxel. Cold Spring Harb Protoc doi: 10.1101/pdb .prot081190.
Following isolation, 20 μg of protein from the MT extract was immunoblotted for detecting B-3-Tubulin (Primary antibody - 1:500 dilution overnight, Secondary antibody (ab6728) - 1: 2000 dilution for 1h).
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Submitted Feb 28 2018

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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