GTPalphaS (aqueous solution), Guanylate cyclase inhibitor (ab146759)

Overview

  • Product name

    GTPalphaS (aqueous solution), Guanylate cyclase inhibitor
  • Description

    Guanylate cyclase inhibitor. GTP analog.
  • Biological description

    Guanylate cyclase inhibitor. GTP analog. Resistant to hydrolysis by Decapping Scavenger pyrophosphatase (DcpS).
  • Purity

    > 95%
  • CAS Number

    81570-51-6
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    539.24
  • Molecular formula

    C10H16N5O13P3S
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Supplied in water (100 mM)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Kowalska J  et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett 19:1921-5 (2009). Read more (PubMed: 19269171) »
  • Metz SA  et al. Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins. Biochem J 295 ( Pt 1):31-40 (1993). Read more (PubMed: 8216234) »
  • Marino MJ  et al. Partial cloning of putative G-proteins modulating mechanotransduction in the ciliate stentor. J Eukaryot Microbiol 48:527-36 (0). Read more (PubMed: 11596917) »

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