Product nameGuanosine, Purine nucleoside
DescriptionPurine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond
- Guanine riboside
Purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). Neuroprotective agent against glutamatergic excitotoxicity by increasing glutamate uptake and decreasing its release.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Bettio LE et al. Guanosine and its role in neuropathologies. Purinergic Signal N/A:N/A (2016). Read more (PubMed: 27002712) »
- Dal-Cim T et al. Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation. Neurotox Res 29:460-8 (2016). Read more (PubMed: 26858177) »
- Cittolin-Santos GF et al. Guanosine Exerts Neuroprotective Effect in an Experimental Model of Acute Ammonia Intoxication. Mol Neurobiol N/A:N/A (2016). Read more (PubMed: 27052954) »
- Kovacs Z et al. Non-adenosine nucleoside inosine, guanosine and uridine as promising antiepileptic drugs: a summary of current literature. Mini Rev Med Chem 14:1033-42 (2015). Read more (PubMed: 25382017) »