GW 590735, PPARalpha agonist (ab144443)
Key features and details
- Potent, selective PPARα agonist
- CAS Number: 622402-22-6
- Purity: > 98%
- Soluble in ethanol to 50 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GW 590735, PPARalpha agonist -
Description
Potent, selective PPARα agonist -
Biological description
Potent, selective PPARα agonist (EC50 = 4 nM). Increases HDL cholesterol, decreases LDL and VLDL cholesterol. Reduces triglycerides. Shows antidyslipidemic effects in vivo. -
Purity
> 98% -
CAS Number
622402-22-6 -
Chemical structure
Properties
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Chemical name
2-Methyl-2-[4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxamido]methyl]phenoxy]propanoic acid -
Molecular weight
478.48 -
Molecular formula
C23H21F3N2O4S -
PubChem identifier
9956726 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 50 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(SC(=N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NCC3=CC=C(C=C3)OC(C)(C)C(=O)O -
Source
Synthetic
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Research areas
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab144443 has not yet been referenced specifically in any publications.
