Overview

  • Product name

    GW1929, PPARgamma agonist
  • Description

    Potent, selective PPARγ agonist
  • Biological description

    Potent, selective PPARγ agonist (EC50 = 8 nM). Decreases glucose, fatty acid and triglyceride levels in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    196808-24-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Kaundal RK & Sharma SS GW1929: a nonthiazolidinedione PPAR? agonist, ameliorates neurological damage in global cerebral ischemic-reperfusion injury through reduction in inflammation and DNA fragmentation. Behav Brain Res 216:606-12 (2011). Read more (PubMed: 20833208) »
  • Nugent C  et al. Potentiation of glucose uptake in 3T3-L1 adipocytes by PPAR gamma agonists is maintained in cells expressing a PPAR gamma dominant-negative mutant: evidence for selectivity in the downstream responses to PPAR gamma activation. Mol Endocrinol 15:1729-38 (2001). Read more (PubMed: 11579205) »
  • Brown KK  et al. A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat. Diabetes 48:1415-24 (1999). Read more (PubMed: 10389847) »
See 1 Publication for this product

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