GW542573X, KCa2 channel activator (ab120502)
Key features and details
- Novel, selective KCa2 channel activator
- CAS Number: 660846-41-3
- Supplied in ethanol (25 mg/ml)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
GW542573X, KCa2 channel activator -
Description
Novel, selective KCa2 channel activator -
Biological description
Novel activator of KCa2 ('SK') channels. Selective SK1 channel activator (EC50 = 8.2 μM). First true activator of KCa2.x and KCa3.1 channels; displays 100-fold greater selectivity for KCa2.x over KCa3.1.
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General notes
Supplied in ethanol (25 mg/ml). Please note this compound is unstable as the solid form and unstable in DMSO
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CAS Number
660846-41-3 -
Chemical structure
Properties
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Chemical name
4-(2-Methoxyphenylcarbamoyloxymethyl)piperidine-1-carboxylic acid tert-butyl ester -
Molecular weight
364.44 -
Molecular formula
C19H28N2O5 -
PubChem identifier
24885053 -
Storage instructions
Store at +4°C (desiccating conditions). -
Solubility overview
Supplied in ethanol (25 mg/ml) -
Handling
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
COc2ccccc2NC(=O)OCC1CCN(CC1)C(=O)OC(C)(C)C -
Source
Synthetic
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Research areas
Images
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Chemical Structure - GW542573X, KCa2 channel activator (ab120502)2D chemical structure image of ab120502, GW542573X, KCa2 channel activator
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab120502 has not yet been referenced specifically in any publications.