Anti-H2R antibody (ab39964)

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Overview

  • Product name

    Anti-H2R antibody
    See all H2R primary antibodies

  • Description

    Goat polyclonal to H2R

  • Host species

    Goat

  • Tested applications

    Suitable for: ICC/IFmore details

  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Dog, Human

  • Immunogen

    Synthetic peptide corresponding to Human H2R aa 335-349 (C terminal).
    Sequence:

    QEEKPLKLQVWSGTE

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 0.5% Tris buffered saline
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab39964 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.

Target

  • Function

    The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • Gastric receptor 1 antibody
    • Gastric receptor I antibody
    • H2R antibody
    • HGNC:5183 antibody
    • HH2R antibody
    • Histamine H2 receptor antibody
    • Histamine receptor H2 antibody
    • HRH2 antibody
    • HRH2_HUMAN antibody
    • OTTHUMP00000161242 antibody
    • OTTHUMP00000161243 antibody
    see all

References

ab39964 has not yet been referenced specifically in any publications.

Publishing research using ab39964? Please let us know so that we can cite the reference in this datasheet.

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