Anti-H2R antibody (ab39964)
- Datasheet
- References
- Protocols
Overview
-
Product nameAnti-H2R antibody
See all H2R primary antibodies -
DescriptionGoat polyclonal to H2R
-
Host speciesGoat
-
Tested applicationsSuitable for: ICC/IFmore details
-
Species reactivityReacts with: Rat
Predicted to work with: Mouse, Dog, Human
-
Immunogen
Synthetic peptide corresponding to Human H2R aa 335-349 (C terminal).
Sequence:QEEKPLKLQVWSGTE
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
-
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 0.5% Tris buffered saline -
Concentration information loading... -
PurityImmunogen affinity purified
-
Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab39964 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF |
Application notes
This antibody gave a positive result in ELISA against the immunizing peptide. Antibody detection limit dilution 1:128,000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
-
FunctionThe H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
-
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
-
Cellular localizationCell membrane.
- Information by UniProt
-
Database links
- Entrez Gene: 3274 Human
- Entrez Gene: 15466 Mouse
- Entrez Gene: 25461 Rat
- Omim: 142703 Human
- SwissProt: P25021 Human
- SwissProt: P97292 Mouse
- SwissProt: P25102 Rat
- Unigene: 247885 Human
see all -
Alternative names
- Gastric receptor 1 antibody
- Gastric receptor I antibody
- H2R antibody
see all
Datasheets and documents
References
ab39964 has not yet been referenced specifically in any publications.
