Overview

  • Product name
    Anti-HAPLN2 antibody
    See all HAPLN2 primary antibodies
  • Description
    Rabbit polyclonal to HAPLN2
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    A 12 amino acid synthetic peptide from near the center of Human HAPLN2 (NP_068589).

  • Positive control
    • Human brain tissue lysate; Human brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab124504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.

Target

  • Function
    Mediates a firm binding of versican V2 to hyaluronic acid. May play a pivotal role in the formation of the hyaluronan-associated matrix in the central nervous system (CNS) which facilitates neuronal conduction and general structural stabilization. Binds to hyaluronic acid.
  • Tissue specificity
    Expressed only in adult brain.
  • Sequence similarities
    Belongs to the HAPLN family.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    Contains 2 Link domains.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • Database links
    see all
  • Alternative names
    • Brain link protein 1 antibody
    • Bral1 antibody
    • Hapln2 antibody
    • HPLN2_HUMAN antibody
    • Hyaluronan and proteoglycan link protein 2 antibody
    see all

Images

  • Western blot - Anti-HAPLN2 antibody (ab124504)
    Western blot - Anti-HAPLN2 antibody (ab124504)
    Lane 1 : Anti-HAPLN2 antibody (ab124504) at 1 µg/ml
    Lane 2 : Anti-HAPLN2 antibody (ab124504) at 2 µg/ml

    All lanes : Human brain tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 37 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HAPLN2 antibody (ab124504)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HAPLN2 antibody (ab124504)
    ab124504, at 2.5 µg/ml, staining HAPLN2 in paraffin-embedded Human brain tissue by Immunohistochemistry.
  • Immunocytochemistry/ Immunofluorescence - Anti-HAPLN2 antibody (ab124504)
    Immunocytochemistry/ Immunofluorescence - Anti-HAPLN2 antibody (ab124504)
    Immunofluorescence of BRAL1 in Human Brain cells using ab124504 at 20 ug/ml.

References

ab124504 has not yet been referenced specifically in any publications.

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