Overview

  • Product name

  • Description

    Rabbit polyclonal to HAS1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human HAS1 (internal sequence). The exact sequence is proprietary.
    Database link: Q92839

  • Positive control

    • Human testis and prostate tissue lysates, Human thyroid cancer tissue
  • General notes

    Protein previously labeled as Hyaluronan synthase 1.

Properties

Applications

Our Abpromise guarantee covers the use of ab198846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/30 - 1/200.
WB 1/200 - 1/1000. Predicted molecular weight: 65 kDa.

Target

  • Function

    Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
  • Tissue specificity

    Widely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
  • Pathway

    Glycan biosynthesis; hyaluronan biosynthesis.
  • Sequence similarities

    Belongs to the NodC/HAS family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • HA synthase 1 antibody
    • HAS antibody
    • HAS1 antibody
    • HuHAS1 antibody
    • Hyaluronan synthase 1 antibody
    • Hyaluronate synthase 1 antibody
    • Hyaluronic acid synthase 1 antibody
    • HYAS1_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling HAS1 with ab198846 at 1/30.

  • All lanes : Anti-HAS1 antibody (ab198846) at 1/350 dilution

    Lane 1 : Human testis tissue lysate
    Lane 2 : Human prostate tissue lysate

    Lysates/proteins at 40 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 65 kDa


    Exposure time: 30 seconds


    Gel: 6%SDS-PAGE

References

ab198846 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198846.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up