Key features and details
- Rabbit polyclonal to HAS1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-HAS1 antibody
See all HAS1 primary antibodies
DescriptionRabbit polyclonal to HAS1
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide within Human HAS1 (internal sequence). The exact sequence is proprietary.
Database link: Q92839
- Human testis and prostate tissue lysates, Human thyroid cancer tissue
Protein previously labeled as Hyaluronan synthase 1.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198846 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/30 - 1/200.|
|WB||1/200 - 1/1000. Predicted molecular weight: 65 kDa.|
FunctionCatalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
Tissue specificityWidely expressed. Highly expressed in ovary followed by spleen, thymus, prostate, testes and large intestine. Weakly expressed in small intestine.
PathwayGlycan biosynthesis; hyaluronan biosynthesis.
Sequence similaritiesBelongs to the NodC/HAS family.
- Information by UniProt
- HA synthase 1 antibody
- HAS antibody
- HAS1 antibody
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling HAS1 with ab198846 at 1/30.
All lanes : Anti-HAS1 antibody (ab198846) at 1/350 dilution
Lane 1 : Human testis tissue lysate
Lane 2 : Human prostate tissue lysate
Lysates/proteins at 40 µg per lane.
Developed using the ECL technique.
Predicted band size: 65 kDa
Exposure time: 30 seconds
ab198846 has been referenced in 2 publications.
- Qi S et al. P38 MAPK signaling pathway mediates COM crystal-induced crystal adhesion change in rat renal tubular epithelial cells. Urolithiasis 48:9-18 (2020). PubMed: 31183507
- Knudtson JF et al. The Hyaluronic Acid System is Intact in Menstrual Endometrial Cells in Women With and Without Endometriosis. Reprod Sci 26:109-113 (2019). PubMed: 29621955