Anti-HB9/HLXB9/MNX1 antibody (ab221884)
- Datasheet
- References
- Protocols
Overview
-
Product name
Anti-HB9/HLXB9/MNX1 antibody
See all HB9/HLXB9/MNX1 primary antibodies -
Description
Rabbit polyclonal to HB9/HLXB9/MNX1 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human HB9/HLXB9/MNX1 aa 6-43.
Sequence:NFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGG
Database link: P50219 -
Positive control
- ICC/IF: MCF7 cells.
-
General notes
This product was previously labelled as HB9/HLXB9
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab221884 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
-
Function
Putative transcription factor involved in pancreas development and function. -
Tissue specificity
Expressed in lymphoid and pancreatic tissues. -
Involvement in disease
Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. -
Sequence similarities
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
-
Database links
- Entrez Gene: 3110 Human
- Omim: 142994 Human
- SwissProt: P50219 Human
- Unigene: 37035 Human
-
Alternative names
- HB 9 antibody
- HB9 antibody
- HLXB 9 antibody
see all
Images
-
Immunocytochemistry/ Immunofluorescence - Anti-HB9/HLXB9/MNX1 antibody (ab221884)PFA-fixed, Triton X-100 permeabilized MCF7 (human breast adenocarcinoma cell line) cells stained for HB9/HLXB9/MNX1 (green) using ab221884 at 4 µg/ml in ICC/IF.
Datasheets and documents
References
ab221884 has not yet been referenced specifically in any publications.
