Anti-HB9/HLXB9/MNX1 antibody (ab221884)
Key features and details
- Rabbit polyclonal to HB9/HLXB9/MNX1
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-HB9/HLXB9/MNX1 antibody
See all HB9/HLXB9/MNX1 primary antibodies -
Description
Rabbit polyclonal to HB9/HLXB9/MNX1 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human HB9/HLXB9/MNX1 aa 6-43.
Sequence:NFRIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGG
Database link: P50219 -
Positive control
- ICC/IF: MCF7 cells.
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General notes
This product was previously labelled as HB9/HLXB9
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab221884 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
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Function
Putative transcription factor involved in pancreas development and function. -
Tissue specificity
Expressed in lymphoid and pancreatic tissues. -
Involvement in disease
Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. -
Sequence similarities
Contains 1 homeobox DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 3110 Human
- Omim: 142994 Human
- SwissProt: P50219 Human
- Unigene: 37035 Human
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Alternative names
- HB 9 antibody
- HB9 antibody
- HLXB 9 antibody
see all
Images
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Immunocytochemistry/ Immunofluorescence - Anti-HB9/HLXB9/MNX1 antibody (ab221884)
PFA-fixed, Triton X-100 permeabilized MCF7 (human breast adenocarcinoma cell line) cells stained for HB9/HLXB9/MNX1 (green) using ab221884 at 4 µg/ml in ICC/IF.
Protocols
References (0)
ab221884 has not yet been referenced specifically in any publications.
