Overview

  • Product name

    Anti-HB9/HLXB9/MNX1 antibody
    See all HB9/HLXB9/MNX1 primary antibodies
  • Description

    Sheep polyclonal to HB9/HLXB9/MNX1
  • Host species

    Sheep
  • Specificity

    The antibody is specific for HB9 in Human and Mouse. This has been confirmed by Immunohistochemical analysis of Normal Term and First Trimester Human Placenta as well as western blot analysis of mouse Neuroblastoma and Spinal Cord cells (NSC-34).
  • Tested applications

    Suitable for: IHC-P, ELISA, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human HB9/HLXB9/MNX1 aa 68-88.
    Sequence:

    APADRLRAESPSPPRLLAAHC

  • Positive control

    • Normal Term and First Trimester Human Placenta and Mouse Neuroblastoma and Spinal Cord cells (NSC-34).
  • General notes

     This product was previously labelled as HB9/HLXB9

     

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab64058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent dilution.
ELISA 1/200 - 1/2600.
WB 1/400. Predicted molecular weight: 41 kDa.

Target

  • Function

    Putative transcription factor involved in pancreas development and function.
  • Tissue specificity

    Expressed in lymphoid and pancreatic tissues.
  • Involvement in disease

    Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
  • Sequence similarities

    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • HB 9 antibody
    • HB9 antibody
    • HLXB 9 antibody
    • HLXB9 antibody
    • Homeo box HB9 antibody
    • Homeobox HB9 antibody
    • Homeobox protein HB9 antibody
    • HOXHB9 antibody
    • MNX1 antibody
    • MNX1_HUMAN antibody
    • Motor neuron and pancreas homeobox 1 antibody
    • Motor neuron and pancreas homeobox protein 1 antibody
    • Sacral agenesis autosomal dominant (Currarino triad) antibody
    • SCRA 1 antibody
    • SCRA1 antibody
    see all

References

ab64058 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Spinal cord at embryonic day e12.5)
Permeabilization
No
Specification
Spinal cord at embryonic day e12.5
Blocking step
Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Fixative
Paraformaldehyde

Dr. Frederic Clotman

Verified customer

Submitted Apr 20 2010

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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