Overview

  • Product name
  • Description
    Rabbit polyclonal to HBP1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human HBP1 aa 470-514 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    DRWKKMKNEER RMYTLEAKAL AEEQKRLNPD CWKRKRTNSG SQQH


    Database link: O60381

  • Positive control
    • WB: Mouse intestine lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab216844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).

Target

  • Function
    Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.
  • Sequence similarities
    Contains 1 AXH domain.
    Contains 1 HMG box DNA-binding domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ16340 antibody
    • HBP 1 antibody
    • HBP1 antibody
    • HBP1_HUMAN antibody
    • High mobility group box transcription factor 1 antibody
    • HMG box containing protein 1 antibody
    • HMG box transcription factor 1 antibody
    • HMG box-containing protein 1 antibody
    see all

Images

  • Anti-HBP1 antibody (ab216844) at 1/200 dilution + mouse intestine lysates

    Secondary
    Goat anti-rabbit IgG antibody (H+L), HRP at 1/3000 dilution

    Predicted band size: 58 kDa

References

ab216844 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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