Anti-HCC1 antibody (ab12326)
Key features and details
- Rabbit polyclonal to HCC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-HCC1 antibody
See all HCC1 primary antibodies -
Description
Rabbit polyclonal to HCC1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Rhesus monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide corresponding to Human HCC1 aa 480-530.
(Peptide available asab40426) -
Positive control
- Nuclear extract from HeLa cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
Purified using the peptide immobilized on solid support. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab12326 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | (1) |
1/1000 - 1/10000. Predicted molecular weight: 59 kDa.
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| Notes |
|---|
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WB
1/1000 - 1/10000. Predicted molecular weight: 59 kDa. |
Target
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Function
Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process. -
Tissue specificity
Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart. -
Sequence similarities
Belongs to the splicing factor SR family.
Contains 3 RRM (RNA recognition motif) domains. -
Cellular localization
Nucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins. - Information by UniProt
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Database links
- Entrez Gene: 508722 Cow
- Entrez Gene: 9584 Human
- Entrez Gene: 170791 Mouse
- Entrez Gene: 100328710 Rabbit
- Entrez Gene: 362251 Rat
- Omim: 604739 Human
- SwissProt: Q14498 Human
- SwissProt: Q8VH51 Mouse
see all -
Alternative names
- CAPER alpha antibody
- CAPER antibody
- CAPERalpha antibody
see all
Images
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Western blot - Anti-HCC1 antibody (ab12326)
Detection of Human Caper by Western Blot. Samples: Nuclear extract (NE) from HeLa cells. Antibody: ab12326 used at 0.3 mcg/ml. Detection: Chemiluminescence with an exposure time of 5 minutes.
Detection of Human Caper by Western Blot. Samples: Nuclear extract (NE) from HeLa cells. Antibody: ab12326 used at 0.3 mcg/ml. Detection: Chemiluminescence with an exposure time of 5 minutes.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab12326 has not yet been referenced specifically in any publications.