Overview

  • Product name
  • Description
    Rabbit polyclonal to HCC1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat, Rabbit, Cow
  • Immunogen

    Recombinant fragment within Human HCC1 (internal sequence). The exact sequence is proprietary.
    Database link: Q14498

  • Positive control
    • WB: NIH/3T3, JC and A431 whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab229238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 59 kDa.

Target

  • Function
    Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process.
  • Tissue specificity
    Widely expressed. Highly expressed in pancreas, skeletal muscle, lung and brain. Expressed at intermediate level in kidney, liver and heart.
  • Sequence similarities
    Belongs to the splicing factor SR family.
    Contains 3 RRM (RNA recognition motif) domains.
  • Cellular localization
    Nucleus speckle. Concentrated in nuclear speckles. Colocalizes with the core spliceosomal snRNP proteins.
  • Information by UniProt
  • Database links
  • Alternative names
    • CAPER alpha antibody
    • CAPER antibody
    • CAPERalpha antibody
    • CC1.3 antibody
    • Coactivator of activating protein 1 and estrogen receptors antibody
    • Coactivator of AP1 and ERs antibody
    • DKFZp781C0423 antibody
    • FLJ44170 antibody
    • HCC 1 antibody
    • Hepatocellular carcinoma protein 1 antibody
    • RBM 39 antibody
    • RBM39 antibody
    • RBM39_HUMAN antibody
    • RNA binding motif protein 39 antibody
    • RNA binding region (RNP1 RRM) containing 2 antibody
    • RNA binding region containing 2 antibody
    • RNA binding region containing protein 2 antibody
    • RNA-binding motif protein 39 antibody
    • RNA-binding protein 39 antibody
    • RNA-binding region-containing protein 2 antibody
    • RNPC 2 antibody
    • RNPC2 antibody
    • Splicing factor CC1.3 antibody
    • Splicing factor CC1.4 antibody
    • Splicing factor HCC 1 antibody
    • Splicing factor HCC1 antibody
    • Transcription coactivator CAPER antibody
    see all

Images

  • All lanes : Anti-HCC1 antibody (ab229238) at 1/1000 dilution

    Lane 1 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate
    Lane 2 : JC whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 59 kDa



    7.5% SDS-PAGE gel.

  • Anti-HCC1 antibody (ab229238) at 1/1000 dilution
    Secondary
    A431 (human epidermoid carcinoma cell line) whole cell lysate at 30 µg

    Predicted band size: 59 kDa



    7.5% SDS-PAGE gel.

References

ab229238 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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