Anti-CGA/hCG alpha antibody [INN-hFSH-132] (ab11232)
Key features and details
- Mouse monoclonal [INN-hFSH-132] to CGA/hCG alpha
- Suitable for: ELISA, IP, WB, RIA, IHC-P
- Reacts with: Human
- Isotype: IgG1
Overview
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Product name
Anti-CGA/hCG alpha antibody [INN-hFSH-132]
See all CGA/hCG alpha primary antibodies -
Description
Mouse monoclonal [INN-hFSH-132] to CGA/hCG alpha -
Host species
Mouse -
Tested applications
Suitable for: ELISA, IP, WB, RIA, IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Chemical/ Small Molecule corresponding to Human CGA/hCG alpha. Human Follicle Stimulating Hormone
Database link: P01215 -
Epitope
ab11232 recognises the alpha 4 epitope of the alpha-subunit of Human Chorionic Gonadotrophin (hCG), hLH, hFSH, hTSH and free alpha-subunit. -
General notes
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Purified IgG prepared by affinity chromatography. -
Clonality
Monoclonal -
Clone number
INN-hFSH-132 -
Myeloma
x63-Ag8.653 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab11232 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ELISA | ||
IP | ||
WB | ||
RIA | ||
IHC-P | (1) |
Notes |
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IHC-P: Used at a dilution of 1/1500 for 2 hrs on human placenta sections (see Abreview for further details).
IP: Use at an assay dependent dilution.
RIA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution (see Berger et al).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Sequence similarities
Belongs to the glycoprotein hormones subunit alpha family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1081 Human
- Omim: 118850 Human
- SwissProt: P01215 Human
- Unigene: 119689 Human
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Alternative names
- Anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG alpha antibody
- CG-alpha antibody
see all
Protocols
Datasheets and documents
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Datasheet download
References (9)
ab11232 has been referenced in 9 publications.
- Zhou J et al. Glycoprotein hormone α-subunit promotes cell proliferation and tumorigenesis in breast cancer. Oncol Lett 23:142 (2022). PubMed: 35340558
- Ogino LL et al. Telomerase expression in clinically non-functioning pituitary adenomas. Endocrine 72:208-215 (2021). PubMed: 33090306
- Kasuki L et al. Accuracy of microcystic aspect on T2-weighted MRI for the diagnosis of silent corticotroph adenomas. Clin Endocrinol (Oxf) 92:145-149 (2020). PubMed: 31773787
- de Almeida Verdolin A et al. Collision sellar lesions: coexistence of pituitary adenoma and Rathke cleft cyst-a single-center experience. Endocrine 68:174-181 (2020). PubMed: 31802354
- Lamback EB et al. Cyclin A in nonfunctioning pituitary adenomas. Endocrine 70:380-387 (2020). PubMed: 32621052
- Adachi K et al. Role of SOX2 in maintaining pluripotency of human embryonic stem cells. Genes Cells : (2010). PubMed: 20384793
- Forbes K et al. Insulin-like growth factor I and II regulate the life cycle of trophoblast in the developing human placenta. Am J Physiol Cell Physiol 294:C1313-22 (2008). IHC-P ; Human . PubMed: 18400990
- Jackson AM et al. The biological action of choriogonadotropin is not dependent on the complete native quaternary interactions between the subunits. Mol Endocrinol 13:2175-88 (1999). PubMed: 10598590
- Berger P et al. Variants of human chorionic gonadotropin from pregnant women and tumor patients recognized by monoclonal antibodies. J Clin Endocrinol Metab 77:347-51 (1993). PubMed: 7688376