Overview

  • Product name

    Anti-hCG antibody [2092]
    See all hCG primary antibodies
  • Description

    Mouse monoclonal [2092] to hCG
  • Host species

    Mouse
  • Specificity

    This antibody reacts with high specificity to ß-HCG. This antibody does not detect FSH or MSH There is a slight reaction with LH
  • Tested applications

    Suitable for: ELISA, IHC-Fr, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Positive control

    • Placenta

Properties

Applications

Our Abpromise guarantee covers the use of ab8466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
IHC-Fr
ICC/IF
IHC-P
  • Application notes
    Cannot be used for RIA with radio-labeled antigen.
    For tissue sections, dilute 1:5-1:25 with PBS
  • Target

    • Relevance

      Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
    • Cellular localization

      Secreted
    • Database links

    • Alternative names

      • anterior pituitary glycoprotein hormones common subunit alpha antibody
      • CG alpha antibody
      • CG-ALPHA antibody
      • CGB antibody
      • CGB3 antibody
      • CGB5 antibody
      • CGB7 antibody
      • choriogonadotropin alpha chain antibody
      • Chorionic gonadotrophin chain beta antibody
      • chorionic gonadotrophin subunit alpha antibody
      • chorionic gonadotropin beta 3 subunit antibody
      • Chorionic gonadotropin beta chain antibody
      • Chorionic gonadotropin beta subunit antibody
      • chorionic gonadotropin, alpha polypeptide antibody
      • chorionic gonadotropin, beta polypeptide 3 antibody
      • chorionic gonadotropin, beta polypeptide antibody
      • Follicle stimulating hormone alpha chain antibody
      • follicle-stimulating hormone alpha chain antibody
      • follicle-stimulating hormone alpha subunit antibody
      • follitropin alpha chain antibody
      • FSH Alpha antibody
      • FSH-alpha antibody
      • FSHA antibody
      • glycoprotein hormones alpha chain antibody
      • glycoprotein hormones, alpha polypeptide antibody
      • GPHa antibody
      • GPHA1 antibody
      • HCG antibody
      • hCGB antibody
      • Human Chorionic Gonadotropin antibody
      • LHA antibody
      • LSH alpha antibody
      • LSH-alpha antibody
      • luteinizing hormone alpha chain antibody
      • lutropin alpha chain antibody
      • Thyroid stimulating hormone alpha chain antibody
      • thyroid-stimulating hormone alpha chain antibody
      • thyrotropin alpha chain antibody
      • TSH Alpha antibody
      • TSH-alpha antibody
      • TSHA antibody
      see all

    References

    This product has been referenced in:

    • Islam K  et al. A Label-Free and Ultrasensitive Immunosensor for Detection of Human Chorionic Gonadotrophin Based on Graphene FETs. Biosensors (Basel) 7:N/A (2017). Read more (PubMed: 28704926) »
    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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