- Datasheet
- Specific References (4)
- Protocols
Overview
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Product nameAnti-hCG antibody
See all hCG primary antibodies -
DescriptionRabbit polyclonal to hCG
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Host speciesRabbit
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SpecificityThis antibody recognises both alpha and beta subunits of hCG.
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Tested applicationsSuitable for: WBmore details
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Species reactivityReacts with: Human
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Immunogen
Purified Chorionic Gonadotropin from human placental glucoprotein urine.
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Positive control
- Purified human CG and rat liver tissue lysate.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
Constituents: 30% Glycerol, 0.5% BSA, PBS, pH 7.2 -
Concentration information loading... -
PurityProtein A purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab54410 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 13 , 18 kDa. (alpha and beta subunits). |
Target
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RelevanceHuman chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.
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Cellular localizationSecreted
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Database links
- Entrez Gene: 1081 Human
- Entrez Gene: 1082 Human
- Omim: 118850 Human
- Omim: 118860 Human
- SwissProt: P01215 Human
- SwissProt: P01233 Human
- Unigene: 119689 Human
- Unigene: 446683 Human
see all -
Alternative names
- anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG alpha antibody
- CG-ALPHA antibody
see all
Protocols
References
This product has been referenced in:
- Li Y et al. Involvement of nephrin in human placental trophoblast syncytialization. Reproduction 149:339-46 (2015). Read more (PubMed: 25614620) »
- Wang R et al. Live cell imaging of in vitro human trophoblast syncytialization. Biol Reprod 90:117 (2014). Read more (PubMed: 24740598) »
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"