Anti-hCG antibody (ab54410)
- Datasheet
- References (6)
- Protocols
Overview
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Product name
Anti-hCG antibody
See all hCG primary antibodies -
Description
Rabbit polyclonal to hCG -
Host species
Rabbit -
Specificity
This antibody recognises both alpha and beta subunits of hCG. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Purified Chorionic Gonadotropin from human placental glucoprotein urine.
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Positive control
- Purified human CG and rat liver tissue lysate.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 30% Glycerol, 0.5% BSA, PBS, pH 7.2 -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab54410 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.5 - 4 µg/ml. Predicted molecular weight: 13 , 18 kDa. (alpha and beta subunits). |
Target
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Relevance
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma. -
Cellular localization
Secreted -
Database links
- Entrez Gene: 1081 Human
- Entrez Gene: 1082 Human
- Omim: 118850 Human
- Omim: 118860 Human
- SwissProt: P01215 Human
- SwissProt: P01233 Human
- Unigene: 119689 Human
- Unigene: 446683 Human
see all -
Alternative names
- anterior pituitary glycoprotein hormones common subunit alpha antibody
- CG alpha antibody
- CG-ALPHA antibody
see all
Protocols
References
This product has been referenced in:
- Lu X et al. Twist1 is involved in trophoblast syncytialization by regulating GCM1. Placenta 39:45-54 (2016). Read more (PubMed: 26992674) »
- Li Y et al. Involvement of nephrin in human placental trophoblast syncytialization. Reproduction 149:339-46 (2015). Read more (PubMed: 25614620) »
