Overview

  • Product name
    Anti-hCG beta 1 epitope antibody [INN-hCG-2]
  • Description
    Mouse monoclonal [INN-hCG-2] to hCG beta 1 epitope
  • Host species
    Mouse
  • Specificity
    Clone INN-hCG-2 is reactive with hCG, hCGbeta, hCGbetacf (fragment), hCGn (nicked), hCGbetan, and CTP-hCG. No cross reaction is observed with hLH, hLHbeta, hFSH, hTSH, or the glycoprotein hormone alpha chains. Affinity constant = 4.8x108 L.mol-1.
  • Tested applications
    Suitable for: IHC-P, ELISA, RIAmore details
    Unsuitable for: Flow Cyt
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human CG.

Properties

Applications

Our Abpromise guarantee covers the use of ab11388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
RIA Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt.
  • Target

    • Relevance
      Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. The beta subunit of chorionic gonadotropin (CG) is encoded by 6 highly homologous genes which are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta subunit gene.
    • Cellular localization
      Secreted
    • Database links
    • Alternative names
      • CG beta antibody
      • CGB antibody
      • Choriogonadotropin subunit beta antibody
      • hCGB antibody

    References

    This product has been referenced in:
    • Woldemariam GA & Butch AW Immunoextraction-tandem mass spectrometry method for measuring intact human chorionic gonadotropin, free ß-subunit, and ß-subunit core fragment in urine. Clin Chem 60:1089-97 (2014). Read more (PubMed: 24899693) »
    See 1 Publication for this product

    Customer reviews and Q&As

    1-2 of 2 Abreviews or Q&A

    Application
    Immunoprecipitation
    Sample
    Human Cell lysate - other (from urine)
    Total protein in input
    50 µg
    Specification
    from urine
    Immuno-precipitation step
    Protein G

    Abcam user community

    Verified customer

    Submitted Oct 22 2011

    Question
    Answer

    DISCOUNT CODE: *** Expiration date: February 15, 2012 I am very pleased to hear you would like to submit an Abreview for ab11388 in IP. This code will give you 1 free primary antibody before the expiration date. To redeem this offer, please submit an Abreview for ab11388 in IP and include this code in the “Additional Comments” section so we know the Abreview is for this promotion. For more information on how to submit an Abreview, please visit the site: www.abcam.com/Abreviews. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code. Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research. The terms and conditions applicable to this offer can be found here: www.abcam.com/collaborationdiscount.  

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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