Anti-hCG beta antibody (ab53087)
Key features and details
- Rabbit polyclonal to hCG beta
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-hCG beta antibody
See all hCG beta primary antibodies -
Description
Rabbit polyclonal to hCG beta -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- NIH/3T3 cell extract; Paraffin embedded human breast carcinoma tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine), PBS
Without Mg+2 and Ca+2 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/300 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
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| IHC-P |
Use at an assay dependent concentration.
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| Notes |
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WB
1/300 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa). |
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IHC-P
Use at an assay dependent concentration. |
Target
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Relevance
Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Tissue specificity: Placenta. Similarity: Belongs to the glycoprotein hormones subunit beta family. Developmental stage: Made by the first trimester placenta. -
Database links
- Entrez Gene: 114336 Human
- Omim: 118860 Human
- Omim: 608824 Human
- SwissProt: P01233 Human
- SwissProt: P0DN86 Human
- SwissProt: P0DN87 Human
- SwissProt: Q6NT52 Human
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Alternative names
- CG beta antibody
- CG-beta antibody
- CgB antibody
see all
Images
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Western blot - Anti-hCG beta antibody (ab53087)All lanes : Anti-hCG beta antibody (ab53087) at 1/300 dilution
Lane 1 : NIH/3T3 cell extract
Lane 2 : NIH/3T3 cell extract with peptide
Predicted band size: 18 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG beta antibody (ab53087)Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using hCG ß antibody, ab53087, at 1/50 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab53087 has been referenced in 6 publications.
- Liu Y et al. Effect of baicalin on gestational hypertension-induced vascular endothelial cell damage. J Int Med Res 48:300060520934288 (2020). PubMed: 33081553
- Karvas RM et al. Use of a human embryonic stem cell model to discover GABRP, WFDC2, VTCN1 and ACTC1 as markers of early first trimester human trophoblast. Mol Hum Reprod 26:425-440 (2020). PubMed: 32359161
- Amaral MS et al. Differential gene expression elicited by ZIKV infection in trophoblasts from congenital Zika syndrome discordant twins. PLoS Negl Trop Dis 14:e0008424 (2020). PubMed: 32745093
- Wu W et al. ß-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway. Cell Cycle 18:46-59 (2019). PubMed: 30582718
- Liu N et al. Human chorionic gonadotropin ß regulates epithelial-mesenchymal transition and metastasis in human ovarian cancer. Oncol Rep 38:1464-1472 (2017). PubMed: 28713970
- McDonald EA & Wolfe MW Adiponectin attenuation of endocrine function within human term trophoblast cells. Endocrinology 150:4358-65 (2009). PubMed: 19520781