Anti-hCG beta antibody (ab53087)
Key features and details
- Rabbit polyclonal to hCG beta
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-hCG beta antibody
See all hCG beta primary antibodies -
Description
Rabbit polyclonal to hCG beta -
Host species
Rabbit -
Specificity
This antibody detects endogenous levels of total hCG beta protein. -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P HumanWB Mouse
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Immunogen
Synthetic peptide derived from human hCG beta.
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Positive control
- NIH/3T3 cell extract; Paraffin embedded human breast carcinoma tissue.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.87% Sodium chloride, 50% Glycerol (glycerin, glycerine), PBS
Without Mg+2 and Ca+2 -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| IHC-P |
Human
|
| WB |
Mouse
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/300 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
|
|
| IHC-P |
Use at an assay dependent concentration.
|
| Notes |
|---|
|
WB
1/300 - 1/1000. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa). |
|
IHC-P
Use at an assay dependent concentration. |
Target
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Relevance
Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Tissue specificity: Placenta. Similarity: Belongs to the glycoprotein hormones subunit beta family. Developmental stage: Made by the first trimester placenta. -
Database links
- Entrez Gene: 114336 Human
- Omim: 118860 Human
- Omim: 608824 Human
- SwissProt: P01233 Human
- SwissProt: P0DN86 Human
- SwissProt: P0DN87 Human
- SwissProt: Q6NT52 Human
- Unigene: 172944 Human
see all -
Alternative names
- CG beta antibody
- CG-beta antibody
- CgB antibody
see all
Images
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Western blot - Anti-hCG beta antibody (ab53087)All lanes : Anti-hCG beta antibody (ab53087) at 1/300 dilution
Lane 1 : NIH/3T3 cell extract
Lane 2 : NIH/3T3 cell extract with peptide
Predicted band size: 18 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG beta antibody (ab53087)Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using hCG ß antibody, ab53087, at 1/50 dilution.
Protocols
References (3)
ab53087 has been referenced in 3 publications.
- Wu W et al. ß-hCG promotes epithelial ovarian cancer metastasis through ERK/MMP2 signaling pathway. Cell Cycle 18:46-59 (2019). PubMed: 30582718
- Liu N et al. Human chorionic gonadotropin ß regulates epithelial-mesenchymal transition and metastasis in human ovarian cancer. Oncol Rep 38:1464-1472 (2017). PubMed: 28713970
- McDonald EA & Wolfe MW Adiponectin attenuation of endocrine function within human term trophoblast cells. Endocrinology 150:4358-65 (2009). PubMed: 19520781
