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ab12169 has been referenced in 44 publications.

  • Joung H  et al. Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis. Exp Mol Med 50:e427 (2018). PubMed: 29328071
  • de la Fuente Revenga M  et al. Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity. Neuropsychopharmacology N/A:N/A (2018). PubMed: 30038413
  • Yoon S  et al. PP2A negatively regulates the hypertrophic response by dephosphorylating HDAC2 S394 in the heart. Exp Mol Med 50:83 (2018). PubMed: 30050113
  • Liu H  et al. Alterations of 63 hub genes during lingual carcinogenesis in C57BL/6J mice. Sci Rep 8:12626 (2018). PubMed: 30135512
  • Rosenberg LH  et al. HDAC3 Regulates the Transition to the Homeostatic Myelinating Schwann Cell State. Cell Rep 25:2755-2765.e5 (2018). PubMed: 30517863
  • Pan B  et al. Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification. J Cell Mol Med 21:2481-2490 (2017). ChIP . PubMed: 28382690
  • Kee HJ  et al. Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models. Korean Circ J 47:392-400 (2017). PubMed: 28567090
  • Griffin EA  et al. Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5. Sci Adv 3:e1701682 (2017). PubMed: 29109977
  • Somanath P  et al. CRISPR-mediated HDAC2 disruption identifies two distinct classes of target genes in human cells. PLoS One 12:e0185627 (2017). PubMed: 28982113
  • Rodnoi P  et al. Neuropeptide Y expression marks partially differentiated ß cells in mice and humans. JCI Insight 2:N/A (2017). ChIP ; Mouse . PubMed: 28614797
  • Yu T  et al. CBX7 is a glioma prognostic marker and induces G1/S arrest via the silencing of CCNE1. Oncotarget 8:26637-26647 (2017). WB . PubMed: 28460453
  • Shearstone JR  et al. Chemical Inhibition of Histone Deacetylases 1 and 2 Induces Fetal Hemoglobin through Activation of GATA2. PLoS One 11:e0153767 (2016). ChIP . PubMed: 27073918
  • Hosokawa H  et al. Akt1-mediated Gata3 phosphorylation controls the repression of IFN? in memory-type Th2 cells. Nat Commun 7:11289 (2016). ChIP . PubMed: 27053161
  • Lutz L  et al. Histone modifiers and marks define heterogeneous groups of colorectal carcinomas and affect responses to HDAC inhibitors in vitro. Am J Cancer Res 6:664-76 (2016). WB, IHC-P ; Human . PubMed: 27152243
  • Choi SY  et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS One 11:e0167340 (2016). Mouse . PubMed: 27902771
  • Kwon DH  et al. MDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification. Nat Commun 7:10492 (2016). PubMed: 26832969
  • Ueda K  et al. Repeated lipopolysaccharide exposure causes corticosteroid insensitive airway inflammation via activation of phosphoinositide-3-kinase d pathway. Biochem Biophys Rep 7:367-373 (2016). PubMed: 28955927
  • Ang YS  et al. Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell 167:1734-1749.e22 (2016). PubMed: 27984724
  • Torres OV  et al. CAMKII-conditional deletion of histone deacetylase 2 potentiates acute methamphetamine-induced expression of immediate early genes in the mouse nucleus accumbens. Sci Rep 5:13396 (2015). ChIP . PubMed: 26300473
  • Liyanage VR  et al. Ethanol deregulates Mecp2/MeCP2 in differentiating neural stem cells via interplay between 5-methylcytosine and 5-hydroxymethylcytosine at the Mecp2 regulatory elements. Exp Neurol 265:102-17 (2015). PubMed: 25620416
  • Kim KB  et al. H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation. Nucleic Acids Res 43:3509-23 (2015). Human . PubMed: 25765655
  • Kapuralin K  et al. STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons. Mol Cell Neurosci 67:104-15 (2015). WB ; Mouse . PubMed: 26101075
  • Boucheron N  et al. CD4(+) T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. Nat Immunol 15:439-48 (2014). PubMed: 24681565
  • Hendrickx A  et al. Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease. PLoS One 9:e99467 (2014). WB, ChIP ; Mouse . PubMed: 24919190
  • Tiwari S  et al. Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol 14:30 (2014). WB, IHC-Fr ; Mouse . PubMed: 25011550
  • Samartzis EP  et al. The Expression of Histone Deacetylase 1, But Not Other Class I Histone Deacetylases, Is Significantly Increased in Endometriosis. Reprod Sci N/A:N/A (2013). Human . PubMed: 23690335
  • Sohal SS  et al. Changes in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: a randomized controlled trial. PLoS One 8:e64833 (2013). IHC-P ; Human . PubMed: 23717666
  • Kerl K  et al. The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells. BMC Cancer 13:286 (2013). WB ; Mouse . PubMed: 23764045
  • Kalthoff S  et al. Gender matters: estrogen receptor alpha (ERa) and histone deacetylase (HDAC) 1 and 2 control the gender-specific transcriptional regulation of human uridine diphosphate glucuronosyltransferases genes (UGT1A). J Hepatol 59:797-804 (2013). ChIP ; Human . PubMed: 23714156
  • Chen A  et al. Lysine deacetylase inhibition promotes relaxation of arterial tone and C-terminal acetylation of HSPB6 (Hsp20) in vascular smooth muscle cells. Physiol Rep 1:e00127 (2013). PubMed: 24400135
  • Kurita M  et al. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nat Neurosci 15:1245-54 (2012). PubMed: 22864611
  • Son HJ  et al. Negative regulation of JAK2 by H3K9 methyltransferase G9a in leukemia. Mol Cell Biol 32:3681-94 (2012). PubMed: 22801367
  • Tarasenko N  et al. Disparate impact of butyroyloxymethyl diethylphosphate (AN-7), a histone deacetylase inhibitor, and doxorubicin in mice bearing a mammary tumor. PLoS One 7:e31393 (2012). WB ; Mouse, Rat . PubMed: 22384017
  • Bahari-Javan S  et al. HDAC1 regulates fear extinction in mice. J Neurosci 32:5062-73 (2012). ChIP . PubMed: 22496552
  • Matsuda KI  et al. Histone Deacetylation during Brain Development Is Essential for Permanent Masculinization of Sexual Behavior. Endocrinology 152:2760-7 (2011). WB, ChIP ; Rat . PubMed: 21586557
  • Ghandhi SA  et al. Time-series clustering of gene expression in irradiated and bystander fibroblasts: an application of FBPA clustering. BMC Genomics 12:2 (2011). WB . PubMed: 21205307
  • Varlakhanova N  et al. Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells. Epigenetics Chromatin 4:20 (2011). ChIP . PubMed: 22053792
  • Chandrasekar V & Dreyer JL The Brain-Specific Neural Zinc Finger Transcription Factor 2b (NZF-2b/7ZFMyt1) Suppresses Cocaine Self-Administration in Rats. Front Behav Neurosci 4:14 (2010). IHC-Fr ; Rat . PubMed: 20407577
  • Guan JS  et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459:55-60 (2009). WB, ChIP, IHC-FoFr ; Mouse . PubMed: 19424149
  • Marquard L  et al. Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas. Histopathology 54:688-98 (2009). IHC-P ; Human . PubMed: 19438744
  • Yamaguchi J  et al. Histone deacetylase inhibitor (SAHA) and repression of EZH2 synergistically inhibit proliferation of gallbladder carcinoma. Cancer Sci : (2009). IHC-P ; Human . PubMed: 19860841
  • Meja KK  et al. Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2. Am J Respir Cell Mol Biol 39:312-23 (2008). PubMed: 18421014
  • Dejligbjerg M  et al. Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells. Mol Cancer 7:70 (2008). WB ; Human . PubMed: 18789133
  • Marquard L  et al. Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology 53:267-77 (2008). PubMed: 18671804

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