Overview

  • Product name

    HEAT hydrochloride (BE2254), alpha1 adrenoceptor antagonist
  • Description

    Highly selective α1 adrenoceptor antagonist
  • Alternative names

    • BE2254
  • Biological description

    Highly selective α1 adrenoceptor antagonist (Ki = 0.53 nM). Precursor of the 3-[125I]-derivative.
  • Purity

    > 99%
  • CAS Number

    30007-39-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Grisanti LA  et al. a1-adrenergic receptors positively regulate Toll-like receptor cytokine production from human monocytes and macrophages. J Pharmacol Exp Ther 338:648-57 (2011). Read more (PubMed: 21571945) »
  • Zhang J  et al. Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: involvement of beta1- and beta2-adrenergic receptors. Am J Physiol Gastrointest Liver Physiol 297:G269-77 (2009). Read more (PubMed: 19460844) »
  • Zhang YY  et al. Alpha(1)-adrenoceptor subtypes mediating inotropic responses in rat heart. J Pharmacol Exp Ther 291:829-36 (1999). Read more (PubMed: 10525106) »

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