Key features and details
- Rabbit polyclonal to Helicobacter pylori
- Suitable for: Flow Cyt, ICC/IF, IHC-P
- Isotype: IgG
Product nameAnti-Helicobacter pylori antibody
See all Helicobacter pylori primary antibodies
DescriptionRabbit polyclonal to Helicobacter pylori
Tested applicationsSuitable for: Flow Cyt, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Other species
Tissue, cells or virus corresponding to Helicobacter pylori. (Total sonicate of Helicobacter pylori).
- Helicobacter pylori infected stomach biopsy.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab187301 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 0.5-1µl for 106 cells.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use a concentration of 1 - 2 µg/ml.|
|IHC-P||Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
RelevanceThe spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
- H. pylori antibody
ab187301 has been referenced in 1 publication.
- Yang Y et al. Role of caspase-3/E-cadherin in helicobacter pylori-induced apoptosis of gastric epithelial cells. Oncotarget 8:59204-59216 (2017). PubMed: 28938629