Key features and details
- Mouse monoclonal [SPM526] to Helicobacter pylori
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG1
Product nameAnti-Helicobacter pylori antibody [SPM526]
See all Helicobacter pylori primary antibodies
DescriptionMouse monoclonal [SPM526] to Helicobacter pylori
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Tissue, cells or virus corresponding to Helicobacter pylori Helicobacter pylori. Purified Helicobacter pylori.
- IHC-P: Human Helicobacter pylori-infected stomach tissue.
This product is FOR RESEARCH USE ONLY. For commercial use, please contact firstname.lastname@example.org.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityProtein A/G purified
Purification notesPurified from TCS by Protein A/G.
Light chain typekappa
Our Abpromise guarantee covers the use of ab231433 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Boil tissue section in Citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes.
Incubate with primary antibody for 30 minutes at room temperature.
RelevanceThe spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
- H. pylori antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab231433 has not yet been referenced specifically in any publications.