Overview

  • Product name

    HELSS, inhibitor of Ca2+ independent PLA2
  • Description

    Potent, irreversible, selective inhibitor of Ca2+ independent PLA2
  • Biological description

    Potent, irreversible, selective inhibitor of Ca2+ independent PLA2 (IC50 = 1 μM). Active in vivo.
  • Purity

    > 98%
  • CAS Number

    88070-98-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Pinet C  et al. Protease-activated receptor-1 mediates thrombin-induced persistent sodium current in human cardiomyocytes. Mol Pharmacol 73:1622-31 (2008). Read more (PubMed: 18326052) »
  • You J  et al. Role of cytoplasmic phospholipase A2 in endothelium-derived hyperpolarizing factor dilations of rat middle cerebral arteries. J Cereb Blood Flow Metab 22:1239-47 (2002). Read more (PubMed: 12368663) »
  • Nethery D  et al. Formation of reactive oxygen species by the contracting diaphragm is PLA(2) dependent. J Appl Physiol 87:792-800 (1999). Read more (PubMed: 10444641) »

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